Bioactive Small Molecules
Medchemexpress LLC HY-112780 100mg , UC2288 CAS:1394011-91-6 Purity:>98%
HY-112780 100mg UC2288 CAS: 1394011-91-6 UC2288 is a novel, cell-permeable, and orally active p21 attenuator (relatively selective activity for p21), which is synthesized based Sorafenib (HY-10201). UC2288 decreases p21 mRNA expression independently of p53, and attenuates p21 protein levels with minimal effect on p21 protein stability. UC2288 has no inhibition of VEGFR2 and Raf kinases even at 10 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-13756 200mg , Tacrolimus CAS:104987-11-3 Purity:>98%
HY-13756 200mg Tacrolimus CAS: 104987-11-3 Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-110251 10mg , DFHBI-1T CAS:1539318-36-9 Purity:>98%
HY-110251 10mg DFHBI-1T CAS: 1539318-36-9 DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0445 500mg , NAD+ CAS:53-84-9 Purity:>98%
HY-B0445 500mg NAD+ CAS: 53-84-9 NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-113071A 50mg , Mevalonic acid (lithium salt) CAS:2618458-93-6 Purity:>98%
HY-113071A 50mg Mevalonic acid (lithium salt) CAS: 2618458-93-6 Mevalonic acid lithium salt, a precursor in the mevalonate pathway, is essential for cell growth and proliferation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-109017 10mg , Vamorolone CAS:13209-41-1 Purity:>98%
HY-109017 10mg Vamorolone CAS: 13209-41-1 Vamorolone (VBP15) is a first-in-class, orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects. Vamorolone shows potent NF-κB inhibition and substantially reduces hormonal effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-120859 10mg , Zidebactam CAS:1436861-97-0 Purity:>98%
HY-120859 10mg Zidebactam CAS: 1436861-97-0 Zidebactam (WCK-5107) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-W021879 50mg , DSRM-3716 CAS:58142-99-7 Purity:>98%
HY-W021879 50mg DSRM-3716 CAS: 58142-99-7 DSRM-3716 (5-Iodoisoquinoline) is a potent and selective SARM1 NADase inhibitor with an IC50 of 75 nM. DSRM-3716 is selective against other NAD+-processing enzymes, receptors, and transporters. DSRM-3716 provides robust axon protection. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-111772 1mg , Elexacaftor CAS:2216712-66-0 Purity:>98%
HY-111772 1mg Elexacaftor CAS: 2216712-66-0 Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). Elexacaftor (VX-445, Compound 1) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-P0216 5mg , A 779 CAS:159432-28-7 Purity:>98%
HY-P0216 5mg A 779 CAS: 159432-28-7 A 779 is a specific antagonist of G-protein coupled receptor (Mas receptor), which is an Ang1-7 receptor distinct from the classical AngII. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-103683 10mg , PF-06409577 CAS:1467057-23-3 Purity:>98%
HY-103683 10mg PF-06409577 CAS: 1467057-23-3 PF-06409577 is a potent and selective allosteric activator of AMPK α1β1γ1 isoform with an EC50 of 7 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Btk inhibitor 2 (BGB-3111 analog) | 1558036-85-3 | MFCD31382019 | 99.6% | 431.49 g/mol | C24H25N5O3 | 10 MG
Btk inhibitor 2 (BGB-3111 analog) is a small-molecule Bruton's tyrosine kinase (BTK) inhibitor described in patent literature and provided for research use. It is supplied as a solid with reported characterization and batch purity data suitable for laboratory assays.
- Potent BTK inhibitor useful for biochemical and cellular assays.
- Supplied as a solid with demonstrated high purity for research applications.
- Soluble in common organic solvents such as DMSO for assay preparation.
- Characterized by molecular formula C24H25N5O3 and molecular weight 431.49 g/mol.
- Available in small milligram pack sizes with batch certificate of analysis.
![Medchemexpress LLC Cyclopropanecarboxylic acid, 2-[4-[bis(2-methylpropyl)amino]-3-[[[(4-methylphenyl)amino]carbonyl)amino]phenyl]-, (1R,2S)- | 1629125-65-0 | 99.9% | 437.57 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385699-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Cyclopropanecarboxylic acid, 2-[4-[bis(2-methylpropyl)amino]-3-[[[(4-methylphenyl)amino]carbonyl)amino]phenyl]-, (1R,2S)- | 1629125-65-0 | 99.9% | 437.57 | 50 MG
BMS-978587 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor, extracted from patent WO2014150677A1, Compound example 1 enantiomer 1. It is for research use only.
- Inhibits IDO-1 in human IDO1/HEK293 cells
Medchemexpress LLC Panidazole | 13752-33-5 | MFCD00866604 | 99.7% | 232.24 g/mol | C11H12N4O2 | 1 ML
Panidazole is an amoebicide provided as a ready-to-use stock solution for laboratory research. The product is supplied as a 10 mM solution in a 1 mL vial and is intended for research use only.
Medchemexpress LLC IL-17A antagonist 3 | 2230780-65-9 | 99.3% | 613.11 | C33H33ClN6O4 | 10 MG
IL-17A antagonist 3 is a small-molecule research compound that antagonizes interleukin-17A, intended for use in inflammation and immunology studies. It is supplied as a solid with formula C33H33ClN6O4, a molecular weight of 613.11, and high confirmed purity for research applications.
- Provides IL-17A antagonism for target validation studies.
- High purity suitable for biochemical and cellular assays.
- Supplied as a solid for convenient storage and handling.
- Molecular formula C33H33ClN6O4 and molecular weight 613.11.
- Recommended storage at 4°C; additional solvent storage conditions documented.
- Available in small research quantities (for example, 10 mg).